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Microenvironmental Sensing by fibroblasts controls tissue composition.
Zhou*, Franklin*, et al., 2022. PNAS.
Fibroblast expression at different stress conditions (sequencing deposit)
Yap1 ChIP (sequencing deposit)
notes: density-dependent genes in fibroblasts were initially determined using sleuth program ( taking into account of batch-to-batch variation), with criteria of > 2 TPM and adjusted p-value < 0.05, fold change > 1.5-fold (1826 genes). To prevent over-fitting, we then added a customized algorithm to evaluate the consistency between biological replicates. In combination of the two, we have identified 1639 density-dependent genes in MEFs.
Circuit Design Features of a Stable Two-cell System.
Zhou*, Franklin*, Adler* et al., 2018. Cell.
Time-course imaging of macrophage-fibroblast co-culture (unpublished data, dropbox link)
Phase portraits and other data used to generate main figures (dropbox link)